A military source close to the government said the army was working to secure the Kweires air base in Aleppo Province, where soldiers and officers have been under attack since 2013.
It is the most high-profile victory for Syria's army since Russia launched an air campaign in support of President Bashar Assad on September 30.
Syrian state media said that Assad congratulated the head of the military air base for the steadfastness of the troops and also the commander of the offensive which broke the siege.