The Endeavour capsule, also making its second flight, was launched into space on Friday atop a SpaceX Falcon 9 rocket from NASA's Kennedy Space Center in Florida. SpaceX is the Elon Musk's commercial rocket company.
The Endeavour docked to the space station complex at 5:08 a.m. EDT (0908 GMT) while the spacecraft were flying 264 miles (425 km) above the Indian Ocean, NASA said in an update on the mission.
On board were two NASA astronauts - mission commander Shane Kimbrough, 53, and pilot Megan McArthur, 49 - along with Japanese astronaut Akihiko Hoshide, 52, and fellow mission specialist Thomas Pesquet, 43, a French engineer from the European Space Agency.
The mission marks the second "operational" space station team launched by NASA aboard a Crew Dragon capsule since human spaceflights resumed from American soil last year, following a nine-year hiatus at the end of the U.S. space shuttle program in 2011.
It is also the third crewed flight launched into orbit in 11 months under NASA's fledgling public-private partnership with SpaceX, the rocket company founded in 2002 by Musk, who is also CEO of electric car maker Tesla Inc.
The mission's Falcon 9 rocket blasted off with the same first-stage booster that lofted a crew into orbit five months ago, marking the first time a previously flown booster has ever been re-used in a crewed launch.
Reusable booster vehicles, designed to fly themselves back to Earth and land safely rather than fall into the sea after launch, are at the heart of a re-usable rocket strategy that SpaceX helped pioneer to make spaceflight more economical.