Republican lawmaker Mike Coffman from Colorado told CBS that Trump should "step aside" and said "his defeat at this point seems almost certain."Trump, known for his unconventional and controversial speaking style, has made a series of gaffes in his campaign but the graphic nature of the clip would hurt his standing among women, independents, and wavering Republicans, said David Yepsen, director of the Paul Simon Public Policy Institute at Southern Illinois University."We've never seen something like this Trump clip in a modern presidential campaign," Yepsen said, calling the incident "sad for the American political system" and for Trump's supporters.Republican strategist Ron Bonjean said "this feels like it is quickly becoming a political 'game over'" for Trump."Unless voters don't care about these issues or believe that this is simply political dirty tricks by releasing the videos now, Trump is going to have to pull a rabbit out of his hat in order to turn things around," Bonjean said.Still, Trump's past controversial comments have failed to shake his core supporters, said David Axelrod, a former political adviser to Democratic President Barack Obama."Appalling as the (Trump) tape is, I'm reminded of all the times we have said, THIS time he's REALLY done," Axelrod said on Twitter.Donald Trump's statements are beyond offensive & despicable. While I cannot vote for Hillary Clinton, I will not vote for Trump. #utpol
— Gary R. Herbert (@HerbertForUtah) October 8, 2016