Ministry spokesman Geng Shuang made the comment at a regular news briefing.
The Republican president, the subject of an impeachment inquiry in the U.S. Congress for asking Ukraine's president to investigate the Bidens, last week suggested that Beijing "start an investigation" into the 2020 presidential hopeful and his son Hunter, who had business interests in China.
Trump has said Biden and his son are "corrupt" but has shown no evidence to back that up.