A new Russian strike on Kharkiv, Ukraine's second largest city, killed two civilians and injured seven early on Saturday, regional Governor Oleh Synehubov said on Telegram.
Suspilne public television said a high-rise apartment building in the Shevchenkivskyi district was damaged and a shop was ablaze. Other news reports said the strike had occurred just after midnight.
Synehubov had earlier reported a strike in Kharkiv on a residential building and a missile attack on a village north of the city. No casualties were reported in either incident.
Kharkiv, in Ukraine's northeast, has been a frequent Russian target, with attacks intensifying in recent weeks. On Wednesday, a drone attack on the city killed four people and badly damaged apartment blocks.