WASHINGTON - The US-led coalition fighting Islamic State said it killed nearly 150 militants in strikes carried out on Saturday in the Syrian middle Euphrates River Valley. 'The precision strikes were a culmination of extensive intelligence preparation to confirm an ISIS headquarters and command and control center in an exclusively ISIS-occupied location in the contested middle Euphrates River Valley,' a statement issued on Tuesday said, using an acronym for Islamic State. The statement said the strikes took place near As Shafah, Syria and killed between 145 and 150 militants.