One inescapable reality of life is the wear and tear on our bodies. A particularly vulnerable area is your joints, the connective sockets where 2 or more bones meet to allow for movement.
The older or more active you are, the more wear and tear on these crucial pressure points.
If you’ve been feeling joint pain or soreness and are looking for the best joint supplement to provide some relief, we may have some suggestions, like GenF20 Red Algae Calcium.
Top Picks
- GenF20 Icelandic Red Algae Calcium – Overall best joint supplement
- Kion Flex – Best supplement for inflammation and joint pain
- Organixx Joint & Muscle Care – Best turmeric supplement for joint pain
- Health Nutrition Joint Care Gummies – Best joint health supplement for fitness
- Health Nutrition Ultra Joint Flex – Best knee joint supplement
- Performance Lab Flex – Best joint supplement for long-term use
- Oweli Move – Best supplement for joint health
- Akasha Naturals Joint Ease – Best joint supplement for vegetarians
- Ancient Nutrition Joint + Mobility – Best joint supplement with collagen
- Dr. Emil Joint Support – Best joint supplement for arthritis
There are a lot of causes of joint pain. Arthritis from aging is the most common, yet even pro athletes can experience inflamed joints from continuous wear and tear. If you’re looking to help regain some of your lost movement, let’s explore what the best supplement for joint pain is for your needs.
1. GenF20 Icelandic Red Algae Calcium – Overall Best Joint Supplement
Money-Back Guarantee: 67 days
Return Policy: 67 days
Cost Per Dosage: $2.00
Pros
- Organic vegan blend
- Clinically studied doses
- Superior absorption
- Beats glucosamine in clinical trials
- 67-day return guarantee
Cons
- Possible shipping delays
Product Overview
GenF20’s Icelandic Red Algae Calcium is formulated to support bone health and reduce joint pain for more flexibility. Recent clinical tests have shown that Aquamin, one of the key ingredients in GenF20 Icelandic Red Algae, significantly outperforms other calcium supplements in head-to-head trials. In fact, after only 14 days, the mineral not only reduced pain in test subjects but also increased their range of motion.
Ingredients
- 1000 mg Calcium (from Aquamin Icelandic Red Algae): Strengthens bones and supports overall joint health by maintaining bone density [1].
- 85 mg Vitamin K2: Directs calcium to bones and away from arteries, improving bone mineralization and joint function [2].
- 96 mg Magnesium: Relaxes muscles and reduces joint stiffness, enhancing overall joint mobility and comfort [3].
- 500 mg Citrus Bioflavonoids: Provides antioxidant support, reducing inflammation and protecting joint tissues from oxidative stress [4].
- 20 mcg Vitamin D3: Enhances calcium absorption and supports bone health, which is crucial for maintaining strong and healthy joints [5].
Dosage
- 3 tablets daily
Pricing
- 1 Month: $59.95
- 3 Months: $159.95
- 6 Months: $299.95
User Reviews
Leading Edge Health holds a strong reputation on Trustpilot with a 4.5 out of 5-star rating from over 1,000 customers. It reflects well on their products and this is one of the best joint supplements with magnesium you can find. That said, some customers express dissatisfaction with the perceived value vs the cost and difficulties in claiming the money-back guarantee.
2. Kion Flex – Best Supplement for Inflammation and Joint Pain
Money-Back Guarantee: 60 days
Return Policy: 60 days
Cost Per Dosage: $1.50
Pros
- Clinically studied ingredients
- Turmerosaccharides for inflammation
- Ayuflex haritaki fruit extract for joint health
- Subscribers get 10% off
Cons
- Contains maltodextrin
Product Overview
Fast-acting Kion Flex is designed to counteract joint pain that results from exercise related activities. Containing all-natural plant-based ingredients, it features the first ever water-soluble form of turmeric root known turmerosaaccharides, specifically for combating inflammation.
Ingredients
- 1000 mg Turmeric Root Extract: Contains curcumin, which reduces joint pain and stiffness through its anti-inflammatory properties [6].
- 500 mg Terminalia Chebula Fruit Extract: Enhances joint mobility and reduces inflammation with its antioxidant effects [7].
- 30 mg Serrapeptase: Decreases inflammation and pain by breaking down damaged tissues, aiding recovery [8].
- 30 mg Protease Enzyme Blend: Supports joint health by improving protein digestion and reducing inflammation [9].
Dosage
- 3 capsules daily on an empty stomach
Pricing
- 1 Month: $44.96 or $39.96 for subscribers
User Reviews
Kion Flex has received favorable reviews on Amazon, scoring 4.4 out of 5 stars from 172 global ratings. Many users have praised the supplement for its quality and effectiveness, particularly noting its benefits for sore joints and improved recovery times. However, some users report little to no improvement in their mobility or reduction in joint discomfort despite regular use.
3. Organixx Joint & Muscle Care – Best Turmeric Supplement for Joint Pain
Money-Back Guarantee: 1 year
Return Policy: 1 year
Cost Per Dosage: $1.83
Pros
- Helps reduce joint pain and decrease inflammation
- No fillers, binders, or excipients
- Vegan capsules
- 1-year money-back guarantee
Cons
- Discounts only for subscribers
Product Overview
Organixx Joint & Muscle Care is a 100% all-natural plant-based product. It contains only organic turmeric, frankincense, and myrrh, 3 scientifically proven inflammation fighters in one formula.
Besides promoting a healthy inflammation response, Organixx supports healthy circulation, heart function, and digestion. It also supports boosting energy and improving emotional balance.
Ingredients
- Fermented Organic Turmeric: Enhances absorption and increases anti-inflammatory properties, helping to reduce joint pain and improve mobility [6].
- Frankincense Extract: Contains boswellic acids that help manage inflammation, improve mobility, and alleviate chronic pain in joints [10].
- Myrrh: Traditionally used for its analgesic and anti-inflammatory properties, it aids in relieving joint pain and swelling [11].
Dosage
- 2 capsules daily with either water or food
Pricing
- 1 Month: $54.95
- Subscribers get 15% off and free shipping
User Reviews
Organixx Joint & Muscle Care has garnered positive feedback on Amazon, holding a 4.4 out of 5-star rating from 208 global ratings. Many users praise its high quality and effectiveness in alleviating arthritis symptoms.
However, some express disappointment, noting no significant change in their pain levels despite its higher price.
4. Health Nutrition Joint Care Gummies – Best Joint Health Supplement for Fitness
Money-Back Guarantee: 100 days
Return Policy: 14 days
Cost Per Dosage: $0.83
Pros
- Made in FDA-registered, GMP-certified facilities
- 100 day money back guarantee
- Free personalized diet and exercise plans
- Always live, human customer service
Cons
- No free shipping without subscribing
Product Overview
Health Nutrition is both an online health store and an interactive health community. It is about providing not only great supplements but also a supportive environment for finding your health goals.
The company’s Joint Care Gummies are a perfect example if you’re looking for the best joint supplement for women and men who are into athletics, health, and keeping fit.
Ingredients
- 160 mg Glucosamine: Aids in the development of cartilage, providing a foundation for joint health and functionality [12].
Dosage
- 2 pieces daily
Pricing
- 1 Bottle (60 gummies): $24.99
- Subscribers save 20%
User Reviews
Health Nutrition Joint Care Gummies currently don't have any reviews on their official website, and they aren't available on Amazon either. If you're considering these gummies, it might be a good idea to ask friends or family if they've tried them or search for independent online reviews.
5. Health Nutrition Ultra Joint Flex – Best Joint Supplement for Knees
Money-Back Guarantee: 100 days
Return Policy: 14 days
Cost Per Dosage: $0.83
Pros
- 100-day money-back guarantee
- Free personalized diet and exercise plans
- Made in FDA-registered, GMP-certified facilities
- Supports cartilage for comfortable movement
Cons
- No free shipping without subscribing
Product Overview
Health Nutrition is about providing not only great supplements, but a supportive environment to find your health goals. As a result, they are as much a health community as an online store.
Whether you’re looking for the best joint supplement for women and men who are into athletics, health, and keeping fit, or another form of nutritional support, Health Nutrition has it all.
Ingredients
- 1500 mg Glucosamine Sulfate: Supports the health and strength of cartilage, helping to maintain joint comfort and mobility [12].
- 200 mg Boswellia Extract: Known for its anti-inflammatory properties, Boswellia extract helps reduce joint pain and improve function [13].
- 150 mg Turmeric: Contains curcumin, which is recognized for its anti-inflammatory effects and potential to alleviate joint pain [6].
Dosage
- Regular Use: 3 capsules daily before a meal
- Faster Relief: 6 capsules daily for the first 2 weeks
Pricing
- 1 Bottle: $24.99
- Subscribers save 20%
User Reviews
Since the Health Nutrition Ultra Joint Flex also lacks reviews on the official website and isn't available on Amazon, it's tough to find direct user feedback about this product. Like with the Joint Care Gummies, if you're considering trying Ultra Joint Flex, reaching out to friends or family who might have experience with it could be helpful.
6. Performance Lab Flex – Best Joint Supplement for Long-Term Use
Money-Back Guarantee: 30 days
Return Policy: 14 days
Cost Per Dosage: $1.63
Pros
- Clean formula
- Suitable for vegans and vegetarians
- Designed for long-term joint health support
Cons
- Contains glucosamine derived from shellfish, which is a strong allergen
Product Overview
Performance Lab Flex provides comprehensive, long-term support for joint health. It combines ingredients known for their benefits in maintaining flexibility, reducing inflammation, and supporting overall joint function.
Ingredients
- 500 mg Glucosamine Sulfate: Supports cartilage health and may help reduce joint pain and stiffness [14].
- 100 mg Methylsulfonylmethane (MSM): Provides sulfur to support joint health and may help reduce inflammation [15].
- 100 mg Boswellia Serrata Extract: Known for its anti-inflammatory properties, potentially helping to reduce joint pain [16].
- 250 mg Curcumin (from Turmeric): Offers potent anti-inflammatory effects [17].
Dosage
- Take 2 capsules daily with food.
Pricing
- One-time purchase: $49.00
- With subscription: $44.10
User Reviews
Performance Lab Flex has received positive feedback from users, with an average rating of around 4 out of 5 stars on Trustpilot. Many users on other plaforms report improved joint flexibility and reduced discomfort after consistent use, but some mention that it took several weeks to notice significant improvements.
7. Oweli Move – Best Supplement for Joint Health
Money-Back Guarantee: 100 days
Return Policy: 100 days
Cost Per Dosage: $1.79
Pros
- Long-term joint protection for any age
- Helps lubricate joints
- Quantity discounts up to 44%
- Includes science-backed ingredients
Cons
- $6.95 shipping for orders under $75
Product Overview
Oweli Move is a complex formula of different extracts designed to help promote long-term joint health, regardless of age. Its glucosamine sulfate-based recipe helps restore and maintain joint flexibility, lubricates and protects joint tissue and cartilage, and helps to reduce inflammation.
Ingredients
- 1500 mg Glucosamine Sulfate: Supports the repair and maintenance of healthy cartilage, reducing joint pain and stiffness [12].
- 200 mg Boswellia Extract: Acts as a powerful anti-inflammatory, helping to reduce swelling and improve joint mobility [13].
- 150 mg Turmeric: Contains curcumin, which has potent anti-inflammatory and antioxidant properties, reducing joint pain and promoting joint health [6].
- 150 mg Chondroitin Sulfate: Enhances the shock-absorbing properties of joint cartilage and helps prevent its breakdown, supporting joint flexibility and comfort [18].
- 25 mg Quercetin: Provides anti-inflammatory and antioxidant benefits, reducing joint inflammation and protecting against oxidative stress [19].
Dosage
- 3 capsules daily
Pricing
- 1 Month: $53.99
- 3 Months: $131.97
- 6 Months: $179.94
User Reviews
Oweli Move boasts a stellar reputation on its official website, with all reviews giving it 5 stars and praising its effectiveness in enhancing exercise performance and reducing knee creaking. However, it's wise to seek additional perspectives to get a more balanced view of the product.
8. Akasha Naturals Joint Ease – Best Joint Supplement for Vegetarians
Money-Back Guarantee: 30 days
Return Policy: 30 days
Cost Per Dosage: $1.03
Pros
- Formulated by Board Certified M.D.’s
- All-natural ingredients
- Subscribers save 15%
- Vegan and vegetarian-friendly supplement
Cons
- Proprietary blend does not disclose individual ingredient amounts
Product Overview
If you’re looking for the best joint supplement that’s all-natural and plant-based, look no further than Akasha Naturals Joint Ease.
Formulated by a team of board-certified naturopathic and Chinese doctors, nutritionists, and nurses, this product is energetically and scientifically sound.
Ingredients
Akasha Naturals Joint Ease contains a 350 mg blend of:
- Tetrase™: Reduces joint inflammation and improves mobility by inhibiting enzymes that degrade cartilage [20].
- Oleanolic Acid: Provides anti-inflammatory and antioxidant effects, supporting joint health and reducing pain [21].
- Rosemary Leaf Extract: Enhances circulation and reduces joint stiffness and pain through its anti-inflammatory properties [22].
Dosage
- 1 soft gel daily with food
Pricing
- 1 Bottle (20 servings): $31 or $26.35 for subscribers
User Reviews
At present, there are no customer reviews for this product.
9. Ancient Nutrition Joint + Mobility – Best Joint Supplement With Collagen
Money-Back Guarantee: 30 days
Return Policy: 30 days
Cost Per Dosage: $1.77
Pros
- Multi-collagen complex formula
- Clinically, peer-reviewed studied ingredients
- Reduces joint discomfort from exercise
- Gluten, dairy, soy, nut, antibiotic, and hormone-free
Cons
- Not vegan or vegetarian
Product Overview
This Joint+ Mobility formula contains 4 different collagen sources to reduce joint tenderness and elicit a healthy inflammation response. It is supported by proven research and peer review studies.
It also contains an added joint and mobility blend from plant sources and roots to support joint function and range of motion.
Ingredients
Multi Collagen Complex (1.7g)
- Hydrolyzed Bovine Hide Collagen Peptides: Supports joint health and improves flexibility by promoting collagen production and repair [23].
- Chicken Bone Broth Protein Concentrate: Provides essential nutrients you’d find in many protein powders with amino acids supporting joint cushioning and mobility [24].
- Eggshell Membrane Collagen: Enhances joint comfort and flexibility by providing naturally occurring joint-supporting compounds like glucosamine and chondroitin [25].
- Hydrolyzed Fish Collagen Peptides: Promotes joint health by supplying bioavailable collagen, aiding in cartilage maintenance and repair [26].
Joint & Mobility Blend (354mg)
- Ginger Root: Reduces inflammation and joint pain due to its natural anti-inflammatory properties [27].
- Turmeric Root: Contains curcumin, which helps reduce joint inflammation and pain while supporting overall joint function [6].
- Organic Fermented Skullcap Aerial Parts: Provides antioxidant and anti-inflammatory benefits that support joint health and reduce discomfort [28].
- Apple Cider Vinegar: Helps maintain a healthy pH balance and supports detoxification, potentially reducing joint pain and inflammation [29].
Dosage
- 3 capsules daily
Pricing
- 1 Month: $52.95
- 3 Months: $142.97
- 6 Months: $270.05
User Reviews
Ancient Nutrition Joint + Mobility has received largely positive reviews on Amazon, with an overall rating of 4.4 out of 5 stars from 3,979 global ratings. Customers appreciate the quality, and many have experienced benefits such as pain relief and improvements in skin, nails, and hair growth. However, opinions vary on whether it offers good value for money.
10. Dr. Emil Joint Support – Best Joint Supplement for Arthritis
Money-Back Guarantee: 90 days
Return Policy: 60 days
Cost Per Dosage: $0.83
Pros
- 20% off your first order when you sign up
- 100% hormone, dairy, gluten, and GMO-free
- Free shipping over $30
Cons
- No free shipping for international orders
Product Review
Dr. Emil’s formula boasts glucosamine for pain and stiffness, chondroitin for preserving cartilage, and turmeric for inflammation. It features the big trio of joint health. This supplement can also help to increase your range of motion, help you recover from injuries, and help you deal with the nagging pains of arthritis.
Ingredients
- 1 g Glucosamine HCI: Supports the maintenance and repair of cartilage, promoting joint flexibility and comfort [12].
- 600 mg Chondroitin Sulfate: Helps reduce joint pain and inflammation by enhancing the shock-absorbing properties of collagen in joints [18].
- 200 mg Methylsulfonylmethane (MSM): Reduces inflammation and supports the formation of collagen and connective tissues, improving joint mobility and reducing pain [30].
- 100 mg Borage Oil Powder: Contains gamma-linolenic acid (GLA) which helps reduce joint inflammation and stiffness [31].
- 100 mg Boswellia Serrata Extract: Alleviates joint pain and inflammation by inhibiting inflammatory enzymes, promoting improved joint function [13].
- 100 mg Turmeric Root: Provides anti-inflammatory benefits and helps reduce joint pain due to its active compound, curcumin [6].
Dosage
- 3 capsules daily
Pricing
- 1 Bottle: $24.95 or $18.71 for subscribers
User Reviews
The review for the Joint Support supplement on the official website is positive, with a single 5-star rating. The user reports significant improvements in arthritis symptoms. They noted that lumps on the joints of their hands have almost disappeared, and pain has been alleviated after a couple of months of use.
However, since this is the only review available on the website, it's advisable to seek out independent reviews online for a more balanced perspective.
What Are Joint Supplements?
Joint supplements are dietary additives that can help treat the symptoms and pain associated with arthritis and strenuous physical activity. There is no clear best joint supplement for men or women, but some effective ones are glucosamine, chondroitin, vitamin D, and methylsulfonylmethane (MSM).
Key Ingredients to Look For in Joint Supplements
When choosing joint supplements, it’s essential to look for ingredients that have been scientifically shown to support joint health. Here are some key ingredients to consider:
Glucosamine
Glucosamine is a natural compound found in bone cartilage, the tough tissue that cushions joints. It may help reduce joint pain and improve joint function in individuals with osteoarthritis.
Chondroitin
Chondroitin is a molecule found in the human body and is part of the cartilage that helps cushion our joints. Often used in combination with glucosamine, it may reduce pain and inflammation and slow the progression of osteoarthritis.
MSM (Methylsulfonylmethane)
MSM is a naturally occurring chemical in the human body, some plants, and animals, including cats and dogs. It is commonly used for the pain and inflammation associated with arthritis.
Turmeric
Turmeric is a flowering plant in the ginger family. Medically, it is believed to lessen various inflammatory conditions in the body.
Omega-3 Fatty Acids
These polyunsaturated fats are important nutrients that the human body cannot produce on its own. Fish, some nuts and seeds, and certain plant oils are good sources of omega-3 fatty acids.
Forms of Joint Supplements
Let’s look at some common forms of joint supplements:
Tablets and Capsules
These are usually gelatin or vegetarian capsules filled with powdered or oil-based supplements. GenF20 Icelandic Red Algae Calcium and Organixx Joint & Muscle Care are some joint supplements that come in tablets and capsules.
Powders
Chondroitin sulfate comes in powdered form to help reduce inflammation. MSM aids in softening joint tissue and promoting healthy tendons and ligaments.
Liquid Supplements
Many feel that glucosamine is better absorbed in liquid form and comes in various flavors.
Gummies
Both glucosamine and chondroitin can be taken as flavored gummies. This is an easy-to-take form of supplement that is popular with many customers and for many purposes, from CBD gummies to weight loss gummies.
How to Choose the Best Joint Supplement
Here’s a guide to help you make an informed decision:
Check for Quality and Purity
Make sure that the best joint supplement for your needs is made from all-natural ingredients, is 3rd party tested, and has no harmful additives or GMOs.
Look for Clinical Evidence
Always follow the science when you’re searching for the best joint supplement. Look for products that have been tested in clinical trials and contain 3rd party-tested ingredients.
Consider Dietary Restrictions and Allergies
If you have any dietary restrictions or allergies, carefully examine the ingredients before determining what the best joint supplement is for you. For example, glucosamine supplements often contain shellfish, which could be problematic if you have a shellfish allergy.
Compare Dosages and Forms
Before deciding on the best joint supplement for you, it would be a good idea to consult with a doctor to determine the best form and dosage to take.
>>Try GenF20 Red Algae Calcium now
Benefits of Joint Supplements
We explore some of the key benefits of joint supplements:
Pain Relief
Joint supplements help with pain by reducing inflammation. Perhaps the best joint supplement for pain is vitamin D, as research has found it lacking in those suffering from rheumatoid arthritis.
Improved Mobility
Joint supplements can sometimes help rebuild cartilage which can increase the flexibility of joints.
Reduced Inflammation
An ingredient like glucosamine can serve to prevent cartilage deterioration, which in turn helps prevent inflammation when bones rub together.
Enhanced Cartilage Health
Joint supplements can support cartilage health by reducing inflammation and providing the nutrients that help rebuild damaged cartilage.
Potential Side Effects of Joint Supplements
While joint supplements can provide significant benefits, they can also have potential side effects, like:
Allergic Reactions
If you are someone with allergies, it would be best to consult with your doctor before deciding on the best joint supplement for you. Certain substances like nuts or shellfish that are in some joint supplements can cause serious allergic reactions that could lead to hospitalization.
Gastrointestinal Issues
Joint supplements like glucosamine and chondroitin sometimes cause certain types of gastrointestinal distress, nausea, and vomiting.
Interactions With Medications
If you’re taking any type of prescription or over-the-counter medication, it’s important to first consult with your doctor before determining what’s the best joint supplement for you.
FAQs About Joint Supplements
Let’s review common questions people ask about the best joint supplements.
How Long Does It Take to See Results?
Results vary among patients, but even the best joint pain supplement can take anywhere from 3 to 8 weeks to experience a noticeable improvement.
Can I Take Joint Supplements With Other Medications?
Before taking any supplement for joint pain, you should always consult with your doctor first if you are already taking any over-the-counter or prescription medications.
Are Joint Supplements Safe for Long-Term Use?
Aside from some mild side effects like bloating, nausea, and constipation, a joint supplement like glucosamine hydrochloride can be taken for as long as 2 years. Other forms, like N-acetyl glucosamine, can be taken for as long as 6 months, but you should always consult your doctor first.
Do I Need a Prescription for Joint Supplements?
No, a prescription is not necessary to buy joint supplements. However, it would be prudent to consult with your doctor before trying any, as some may cause harmful side effects.
Can Joint Supplements Prevent Arthritis?
Some joint supplements can help with arthritis symptoms like inflammation and joint stiffness, but there’s currently no scientific proof that any supplement can cure arthritis.
Conclusion on the Best Joint Supplement
There’s no scientific cure for arthritis, but there are options available to alleviate some of the pain and symptoms.
Whether you’re looking for the best joint supplement for runners or the best joint supplement for seniors, hopefully, we’ve given you some safe and effective choices, like GenF20 Red Algae Calcium, to help.
Just remember, before deciding on the best OTC supplement for joint pain, be sure to first consult with your doctor to make sure it is safe for you.
>>Try GenF20 Red Algae Calcium now
References:
- Lau, E. M., Woo, J., Leung, P. C., Swaminathan, R., & Leung, D. (1992). The effects of calcium supplementation and exercise on bone density in elderly Chinese women. Osteoporosis International: A Journal Established as Result of Cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2(4), 168–173. https://doi.org/10.1007/bf01623922
- Schwalfenberg, G. K. (2017). Vitamins K1 and K2: The emerging group of vitamins required for human health. Journal of Nutrition and Metabolism, 2017, 6254836. https://doi.org/10.1155/2017/6254836
- Kuang, X., Chiou, J., Lo, K., & Wen, C. (2021). Magnesium in joint health and osteoarthritis. Nutrition Research (New York, N.Y.), 90, 24–35. https://doi.org/10.1016/j.nutres.2021.03.002
- Oben, J., Enonchong, E., Kothari, S., Chambliss, W., Garrison, R., & Dolnick, D. (2009). Phellodendron and Citrus extracts benefit joint health in osteoarthritis patients: a pilot, double-blind, placebo-controlled study. Nutrition Journal, 8(1), 38. https://doi.org/10.1186/1475-2891-8-38
- Wang, R., Wang, Z.-M., Xiang, S.-C., Jin, Z.-K., Zhang, J.-J., Zeng, J.-C., Tong, P.-J., & Lv, S.-J. (2023). Relationship between 25-hydroxy vitamin D and knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials. Frontiers in Medicine, 10, 1200592. https://doi.org/10.3389/fmed.2023.1200592
- Prasad, S., & Aggarwal, B. B. (2011). Turmeric, the Golden Spice. CRC Press/Taylor & Francis.
- Pokuri, V. K., Kumar, C. U., & Pingali, U. (2016). A randomized, double-blind, placebo-controlled, cross-over study to evaluate analgesic activity of Terminalia chebula in healthy human volunteers using a mechanical pain model. Journal of Anaesthesiology, Clinical Pharmacology, 32(3), 329–332. https://doi.org/10.4103/0970-9185.173365
- Tiwari, M. (2017). The role of serratiopeptidase in the resolution of inflammation. Asian Journal of Pharmaceutical Sciences, 12(3), 209–215. https://doi.org/10.1016/j.ajps.2017.01.003
- Bolten, W. W., Glade, M. J., Raum, S., & Ritz, B. W. (2015). The safety and efficacy of an enzyme combination in managing knee osteoarthritis pain in adults: a randomized, double-blind, placebo-controlled trial. Arthritis, 2015, 251521. https://doi.org/10.1155/2015/251521
- Su, S., Duan, J., Chen, T., Huang, X., Shang, E., Yu, L., Wei, K., Zhu, Y., Guo, J., Guo, S., Liu, P., Qian, D., & Tang, Y. (2015). Frankincense and myrrh suppress inflammation via regulation of the metabolic profiling and the MAPK signaling pathway. Scientific Reports, 5(1), 13668. https://doi.org/10.1038/srep13668
- Batiha, G. E.-S., Wasef, L., Teibo, J. O., Shaheen, H. M., Zakariya, A. M., Akinfe, O. A., Teibo, T. K. A., Al-Kuraishy, H. M., Al-Garbee, A. I., Alexiou, A., & Papadakis, M. (2023). Commiphora myrrh: a phytochemical and pharmacological update. Naunyn-Schmiedeberg’s Archives of Pharmacology, 396(3), 405–420. https://doi.org/10.1007/s00210-022-02325-0
- Veronese, N., Demurtas, J., Smith, L., Reginster, J.-Y., Bruyère, O., Beaudart, C., Honvo, G., Maggi, S., & on behalf on the European Geriatric Medicine Society Special Interest Groups. (2020). Glucosamine sulphate: an umbrella review of health outcomes. Therapeutic Advances in Musculoskeletal Disease, 12. https://doi.org/10.1177/1759720X20975927
- Siddiqui, M. Z. (2011). Boswellia serrata, a potential antiinflammatory agent: an overview. Indian Journal of Pharmaceutical Sciences, 73(3), 255–261. https://doi.org/10.4103/0250-474X.93507
- Martins JMS, Dos Santos Neto LD, Sgavioli S, Araújo ICS, Reis AAS, Santos RS, de Araújo EG, Leandro NSM, Café MB. Effect of glycosaminoglycans on the structure and composition of articular cartilage and bone of broilers. Poult Sci. 2023 Oct;102(10):102916. doi: 10.1016/j.psj.2023.102916. Epub 2023 Jul 1. PMID: 37499613; PMCID: PMC10393804.
- Butawan M, Benjamin RL, Bloomer RJ. Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement. Nutrients. 2017 Mar 16;9(3):290. doi: 10.3390/nu9030290. PMID: 28300758; PMCID: PMC5372953.
- Kumar R, Singh S, Saksena AK, Pal R, Jaiswal R, Kumar R. Effect of Boswellia Serrata Extract on Acute Inflammatory Parameters and Tumor Necrosis Factor-α in Complete Freund's Adjuvant-Induced Animal Model of Rheumatoid Arthritis. Int J Appl Basic Med Res. 2019 Apr-Jun;9(2):100-106. doi: 10.4103/ijabmr.IJABMR_248_18. PMID: 31041173; PMCID: PMC6477955.
- Peng Y, Ao M, Dong B, Jiang Y, Yu L, Chen Z, Hu C, Xu R. Anti-Inflammatory Effects of Curcumin in the Inflammatory Diseases: Status, Limitations and Countermeasures. Drug Des Devel Ther. 2021 Nov 2;15:4503-4525. doi: 10.2147/DDDT.S327378. PMID: 34754179; PMCID: PMC8572027.
- Henrotin, Y., Mathy, M., Sanchez, C., & Lambert, C. (2010). Chondroitin sulfate in the treatment of osteoarthritis: from in vitro studies to clinical recommendations. Therapeutic Advances in Musculoskeletal Disease, 2(6), 335–348. https://doi.org/10.1177/1759720X10383076
- Wang, Haiyan, et al. “Quercetin Prevents Osteoarthritis Progression Possibly via Regulation of Local and Systemic Inflammatory Cascades.” Journal of Cellular and Molecular Medicine, vol. 27, no. 4, 2023, pp. 515–528, doi:10.1111/jcmm.17672.
- Henrotin, Yves, and Ali Mobasheri. “Natural Products for Promoting Joint Health and Managing Osteoarthritis.” Current Rheumatology Reports, vol. 20, no. 11, 2018, doi:10.1007/s11926-018-0782-9.
- Ayeleso, Taiwo, et al. “Oleanolic Acid and Its Derivatives: Biological Activities and Therapeutic Potential in Chronic Diseases.” Molecules (Basel, Switzerland), vol. 22, no. 11, 2017, p. 1915, doi:10.3390/molecules22111915.
- Gonçalves, Catarina, et al. “Potential Anti-Inflammatory Effect of Rosmarinus Officinalis in Preclinical in Vivo Models of Inflammation.” Molecules (Basel, Switzerland), vol. 27, no. 3, 2022, p. 609, doi:10.3390/molecules27030609.
- Khatri, Mishti, et al. “The Effects of Collagen Peptide Supplementation on Body Composition, Collagen Synthesis, and Recovery from Joint Injury and Exercise: A Systematic Review.” Amino Acids, vol. 53, no. 10, 2021, pp. 1493–1506, doi:10.1007/s00726-021-03072-x.
- Hawkins, Jordan, and Paul Durham. “Enriched Chicken Bone Broth as a Dietary Supplement Reduces Nociception and Sensitization Associated with Prolonged Jaw Opening.” Journal of Oral & Facial Pain and Headache, vol. 32, no. 2, 2018, pp. 208–215, doi:10.11607/ofph.1971.
- Ruff, Kevin J., et al. “Eggshell Membrane in the Treatment of Pain and Stiffness from Osteoarthritis of the Knee: A Randomized, Multicenter, Double-Blind, Placebo-Controlled Clinical Study.” Clinical Rheumatology, vol. 28, no. 8, 2009, pp. 907–914, doi:10.1007/s10067-009-1173-4.
- Martínez-Puig, Daniel, et al. “Collagen Supplementation for Joint Health: The Link between Composition and Scientific Knowledge.” Nutrients, vol. 15, no. 6, 2023, p. 1332, doi:10.3390/nu15061332.
- Altman, R. D., and K. C. Marcussen. “Effects of a Ginger Extract on Knee Pain in Patients with Osteoarthritis.” Arthritis and Rheumatism, vol. 44, no. 11, 2001, pp. 2531–2538, doi:10.1002/1529-0131(200111)44:11<2531::aid-art433>3.0.co;2-j.
- Shin, Hee, et al. “Skullcap (Scutellaria Baicalensis) Extract and Its Active Compound, Wogonin, Inhibit Ovalbumin-Induced Th2-Mediated Response.” Molecules (Basel, Switzerland), vol. 19, no. 2, 2014, pp. 2536–2545, doi:10.3390/molecules19022536.
- Bartkiene, Elena, et al. “Multifunctional Nutraceutical Composition Based on Fermented Spirulina, Apple Cider Vinegar, Jerusalem Artichoke, and Bovine Colostrum.” Foods (Basel, Switzerland), vol. 12, no. 8, 2023, p. 1690, doi:10.3390/foods12081690.
- Toguchi, Akifumi, et al. “Methylsulfonylmethane Improves Knee Quality of Life in Participants with Mild Knee Pain: A Randomized, Double-Blind, Placebo-Controlled Trial.” Nutrients, vol. 15, no. 13, 2023, p. 2995, doi:10.3390/nu15132995.
- Kast, Richard E. “Borage Oil Reduction of Rheumatoid Arthritis Activity May Be Mediated by Increased cAMP That Suppresses Tumor Necrosis Factor-Alpha.” International Immunopharmacology, vol. 1, no. 12, 2001, pp. 2197–2199, doi:10.1016/s1567-5769(01)00146-1.
Disclaimer: Content quality approved by JPost.
JPost oversees the native, paid, and sponsored content on this website and guarantees quality, relevance, and value for the audience. However, articles attributed to this byline are provided by paying advertisers and the opinions expressed in the content do not necessarily express the opinions of JPost.
The sponsor retains the responsibility of this content and has the copyright of the material. For all health concerns, it is best to seek the advice of your doctor or a legal practitioner.