There were also several direct hits in the southern city of Ashkelon on Friday.
Magen David Adom forces are searching the building in fear of civilians trapped in the rubble.
A Tuesday afternoon barrage from the Gaza Strip was reportedly the largest in number aimed at Tel Aviv since the start of Operation Swords of Iron.
A home in the settlement, located on the western edge of the Seam Line, was damaged.
The Media Line sat down with Maj. (res.) Libby Weiss, spokesperson for the IDF to delve into the role and effectiveness of the Iron Dome and the challenges the IDF faces.
The majority of Sderot's 30,000 inhabitants left the city after a week of barrages from the Strip that caused a great deal of damage to homes and a number of civilian casualties.
Seven different homes in Sderot were directly hit during the most recent barrage of rockets from Gaza, MDA said.
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