One of the terrorists killed was involved in the shooting attack that led to the murder of an Israeli civilian, Amnon Muchtar, in June.
The police and Shin Bet further added that the alertness levels had been raised throughout Gush Dan, and searches were being carried out in the area.
There is reportedly one casualty at the scene.
During searches by emergency services, the body of a lifeless man was found in an apartment near the location of the explosion.
Palestinian media reports claim that five people were killed in the strike on the Nur Shams camp.
Security sources say some of the arms are bound for the neighboring West Bank, adding that they have arrested several Jordanians linked to Palestinian militants.
Most of the clandestine flow of arms into the country has been bound for the neighboring West Bank, Jordanian officials say.
Police suspect the case, which left a 20-year-old woman dead and a young girl critically injured, may be an assassination attempt on an individual known to the police.
Two different explosive devices were detonated at the checkpoint on Saturday evening, according to the Iraqi Security Media Cell.
One person is reported dead according to a Syrian human rights organization based in the UK.